Job Description

Who we are: 20bloc, Inc. ( is an early-stage biopharma company creating breakthrough protein-based drugs to save lives. We are developing a safe and effective hemoglobin-based oxygen carrier for first response, organ preservation and oxygen therapy. We value and encourage innovations through robust information exchange, hard work, and team interaction. We are collaborative. We are intellectual. We are hands-on.

Job Title: Protein Scientist (Molecular Biology)

Position Overview: We are seeking an experienced Protein Scientist with a background in molecular biology and hands-on experience in genetic engineering and yeast-based expression systems.

Key responsibilities:

• Design, construct and optimize innovative recombinant expression systems with yeast such as Pichia/ komagataella phaffii and Saccharomyces strains to produce high-level expression of target proteins.
• Characterize genetic and phenotypic engineered strains, and analyze expression levels, post-translational modifications, and product quality.
• Collaborate with fermentation scientists to integrate molecular biology work with bioprocess development and production scale-up.
• Identify, qualify and manage CROs and coordinate with partners.
• Write detailed experimental records, scientific reports and presentations.

Requirements :

• PhD in Molecular Biology, Biotechnology, Genetics, Biochemistry, or a related field
• 2+ years of industry experience working directly on genetic engineering.
• Track record in molecular cloning, gene editing, vector design, transformation, strain screening, and optimization of yeast expression systems.
• Proficiency in analytical methods to assess protein expression and quality, such as ELISA, flow cytometry, or glycan analysis.
• Strong planning and problem-solving skills and ability to work both independently and collaboratively in a multidisciplinary team.
• Excellent communication skills, with a proven ability to document research findings and present and interpret complex data and findings concisely and clearly.

This is an excellent opportunity for a motivated individual to grow and excel in an early-stage biopharma company to develop a groundbreaking drug that could make an impact to the life of many. This is a full time position on-site in Thousand Oaks, CA.

20bloc is an equal opportunity employer. We offer a comprehensive benefits package which includes:

• Medical, dental and vision plans
• 120 hours paid time off (PTO)
• 12 paid holidays annually
• 401(k) U.S. retirement savings plan
• Employee assistance program

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